The JPS Tanakh of Isaiah 49:7 reads, in part:
Thus said the LORD,
The Redeemer of Israel, his Holy One,
b-To the despised one,
To the abhorred nations,-b . . .
Note b reads: Meaning of Heb. uncertain. Emendation yields “Whose being is despised / Whose body is detested”; cf. 51.23.
I noticed this first when I read this in Hebrew, and found that I was not able to produce a translation that I found satisfactory. I remained in doubt. So I looked it up in a few translations. Note also that the reading adopted in the JPS text is itself an emendation.